{"id":383,"date":"2013-02-27T18:59:19","date_gmt":"2013-02-27T18:59:19","guid":{"rendered":"http:\/\/www.nicolelislab.net\/?p=383"},"modified":"2013-02-27T18:59:19","modified_gmt":"2013-02-27T18:59:19","slug":"simultaneous-top-down-modulation-of-the-primary-somatosensory-cortex-and-thalamic-nuclei-during-active-tactile-discrimination","status":"publish","type":"post","link":"http:\/\/www.nicolelislab.net\/?p=383","title":{"rendered":"Simultaneous Top-down Modulation of the Primary Somatosensory Cortex and Thalamic Nuclei during Active Tactile Discrimination"},"content":{"rendered":"<p><a href=\"http:\/\/www.nicolelislab.net\/wp-content\/uploads\/2013\/02\/JNeurosci_Feb2013.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-384\" title=\"JNeurosci_Feb2013\" src=\"http:\/\/www.nicolelislab.net\/wp-content\/uploads\/2013\/02\/JNeurosci_Feb2013.jpg\" alt=\"\" width=\"262\" height=\"324\" srcset=\"http:\/\/www.nicolelislab.net\/wp-content\/uploads\/2013\/02\/JNeurosci_Feb2013.jpg 262w, http:\/\/www.nicolelislab.net\/wp-content\/uploads\/2013\/02\/JNeurosci_Feb2013-242x300.jpg 242w, http:\/\/www.nicolelislab.net\/wp-content\/uploads\/2013\/02\/JNeurosci_Feb2013-230x284.jpg 230w, http:\/\/www.nicolelislab.net\/wp-content\/uploads\/2013\/02\/JNeurosci_Feb2013-200x247.jpg 200w, http:\/\/www.nicolelislab.net\/wp-content\/uploads\/2013\/02\/JNeurosci_Feb2013-130x160.jpg 130w\" sizes=\"auto, (max-width: 262px) 100vw, 262px\" \/><\/a>The rat somatosensory system contains multiple thalamocortical loops (TCLs) that altogether process, in fundamentally different ways, tactile stimuli delivered passively or actively sampled. To elucidate potential top-down mechanisms that governTCLprocessing in awake, behaving animals, we simultaneously recorded neuronal ensemble activity across multiple cortical and thalamic areas while rats performed an active aperture discrimination task&#8230;<a href=\"http:\/\/www.nicolelislab.net\/wp-content\/uploads\/2013\/02\/JNeurosci_Vieira2013.pdf\" target=\"_blank\">Read Full Article Here<\/a><\/p>\n<div id=\"caption\"><em>Cover legend:<\/em> As a rat is about to sample a tactile discriminanda in complete darkness solely using its whiskers, multiple anticipatory modulations occur in the somatosensory cortex and thalamus. These modulations (represented in red in the color-coded activity map) originate in M1 and are good predictors of speed and tactile performance. These simultaneous top-down modulations observed in multiple trigeminal pathways indicate that the trigeminal system does not operate based on a labeled line scheme. Cover design by Katie Zhuang, Nicolelis Labs. For more information, see the article by Pais-Vieira et al. (pages\u00a0<a href=\"http:\/\/www.jneurosci.org\/content\/33\/\/lookup\/volpage\/33\/4076?iss=9\" target=\"_blank\">4076\u20134093<\/a>).<\/div>\n<hr \/>\n","protected":false},"excerpt":{"rendered":"<p>The rat somatosensory system contains multiple thalamocortical loops (TCLs) that altogether process, in fundamentally different ways, tactile stimuli delivered passively or actively sampled. To elucidate potential top-down mechanisms that governTCLprocessing in awake, behaving animals, we simultaneously recorded neuronal ensemble activity &hellip; <a href=\"http:\/\/www.nicolelislab.net\/?p=383\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":384,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-383","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-recent-findings"],"_links":{"self":[{"href":"http:\/\/www.nicolelislab.net\/index.php?rest_route=\/wp\/v2\/posts\/383","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.nicolelislab.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.nicolelislab.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.nicolelislab.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.nicolelislab.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=383"}],"version-history":[{"count":9,"href":"http:\/\/www.nicolelislab.net\/index.php?rest_route=\/wp\/v2\/posts\/383\/revisions"}],"predecessor-version":[{"id":394,"href":"http:\/\/www.nicolelislab.net\/index.php?rest_route=\/wp\/v2\/posts\/383\/revisions\/394"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.nicolelislab.net\/index.php?rest_route=\/wp\/v2\/media\/384"}],"wp:attachment":[{"href":"http:\/\/www.nicolelislab.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=383"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.nicolelislab.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=383"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.nicolelislab.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=383"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}